320列CT装置を用いた肺定位放射線治療における標的の軌跡解析

Multi-detector computed tomography (MDCT) has rapidly evolved and is increasingly used for treatment simulation of thoracic and abdominal radiotherapy. A 320-detector row CT scanner has recently become available that allows axial volumetric scanning of a 16-cm-long range in a patient without table movement. Current radiotherapy techniques require a generous margin around the presumed gross tumor volume (GTV) to account for uncertainties such as tumor motion and set up error. Motion analysis is useful to evaluate the internal margin of a moving target due to respiration and to improve therapeutic precision. The purpose of this study is to propose a method using phase-only correlation to automatically detect the target and to assess the motion of the target in numerical phantoms and patients. Free-breathing scans using 320-detector row CT were acquired for 4 patients with lung tumor(s). The proposed method was feasible for motion analysis of all numerical phantoms and patients. The results reproduced the facts that the motion of tumors in the patients varied in orbits during the respiratory cycle and exhibited hysteresis. The maximum distance between peak exhalation and inhalation increased as the tumors approached the diaphragm. The proposed method detected the three-dimensional position of the targets automatically and analyzed the trajectories. The tumor motion due to respiration differed by region and was greatest for the lower lobe.

書誌情報

日本放射線技術学会雑誌

巻 67, 号 3, p. 202-211, 発行日 2011-03

ISSN

収録物識別子タイプ

ISSN

収録物識別子

03694305

書誌レコードID

収録物識別子タイプ

NCID

収録物識別子

AN00197784

著者版フラグ

出版タイプ

VoR

出版タイプResource

http://purl.org/coar/version/c_970fb48d4fbd8a85

その他のタイトル

Motion Analysis of Target in Stereotactic Radiotherapy of Lung Tumors Using 320-row Multidetector CT

出版者

日本放射線技術学会

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2023-06-19 18:01:15.715087

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