@article{oai:tokyo-metro-u.repo.nii.ac.jp:00004432,
 author = {サナダ, キヨシ and ミドリカワ, タイシ and アベ, タカシ and 真田, 樹義 and 緑川, 泰史 and 安部, 孝 and Sanada, Kiyoshi and Kearns, Charles F. and Midorikawa, Taishi and Abe, Takashi},
 issue = {1},
 journal = {European Journal Of Applied Physiology},
 month = {},
 note = {The present study was performed to develop regression-based prediction equations for skeletal muscle (SM) mass by ultrasound and to investigate the validity of these equations in Japanese adults. Seventy-two Japanese men (n=38) and women (n=34) aged 18-61 years participated in this study and were randomly separated into two groups: the model development group (n=48) and the validation group (n=24). The total and regional SM mass were measured using magnetic resonance imaging (MRI) 1.5 T-scanners with spin-echo sequence. Contiguous transverse images (about 150 slices) with a slice thickness of 1 cm were obtained from the first cervical vertebra to the ankle joints. The volume of SM was calculated from the summation of digitized cross-sectional area. The SM volume was converted into mass units (kg) by an assumed SM density of 1.04 kg l^＜-1＞. The muscle thickness (MTH) was measured by B-mode ultrasound (5 MHz scanning head) at nine sites on the anatomical SM belly. Strong correlations were observed between the site-matched SM mass (total, arm, trunk body, thigh, and lower leg) by MRI measurement and the MTH×height (in m) in the model development group (r=0.83-0.96 in men, r=0.53-0.91 in women, P＜0.05). When the SM mass prediction equations were applied to the validation group, significant correlations were also observed between the MRI-measured and predicted SM mass (P＜0.05). The predicted total SM mass for the validation group was 19.6 (6.5) kg and was not significantly different from the MRI-measured SM mass of 20.2 (6.5) kg. Bland-Altman analysis did not indicate a bias in prediction of the total SM mass for the validation group (r=0.00, NS). These results suggested that ultrasoundderived prediction equations are a valid method to predict SM mass and an alternative to MRI measurement in healthy Japanese adults.},
 pages = {24--31},
 title = {Prediction and validation of total and regional skeletal muscle mass by ultrasound in japanese adults},
 volume = {96},
 year = {2006}
}