@article{oai:tokyo-metro-u.repo.nii.ac.jp:00004273, author = {キタムラ, ヒデアキ and コウノ, ユズル and ムラノ, タケシ and ヒロイ, ケンタ and イハラ, カンユウ and アソウ, トモヒコ and イノウエ, カズマサ and フクシ, マサヒロ and Kitamura, Hideaki and Kono, Yuzuru and Murano, Takeshi and Hiroi, Kenta and Ihara, Kanyu and Aso, Tomohiko and Inoue, Kazumasa and Fukushi, Masahiro}, issue = {6}, journal = {Nuclear Medicine Communications}, month = {Jan}, note = {Objectives: Number of lymph nodes to be removed are determined from residual counts. Estimating residual radioactivity in lymphatic nodes before a biopsy in advance is useful for reducing surgical operation time. The purpose of this study was to estimate total radioactivity of a small hot spot in single-photon emission computed tomography (SPECT) of a torso phantom. Methods: Cross-calibration study was performed to convert counts in SPECT images to radioactivity. A simulation study was performed to estimate the size of volume of interest (VOI) covering a hot spot corrupted with full width at half maximum (FWHM) between 8 and 16 mm. The estimation of total radioactivity was validated in a torso phantom study using small sources. Results: True radioactivity was approximately equal to integrated values of hot spots using the VOI with a diameter of 40 mm in our simulation study. The difference was less than18% in cases of more than 9.4 kBq. Conclusions: The total radioactivity in small sources simulating a typical sentinel node was estimated from SPECT images using a VOI of 40 mm in a torso phantom study. Because the difference from actual values were less than 10% on average when radioactivities were more than 9.4 kBq, the total radioactivity of a lymph node can be estimated in a clinical examination., Article}, pages = {646--650}, title = {Estimation of radioactivity in single photon emission computed tomography for sentinel lymph node biopsy in a torso phantom study}, volume = {36}, year = {2015} }